Industrial Biotechnology

Delft University of Technology via edX

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Provider

edX
Pricing

Free Online Course (Audit)
Languages

English
Certificate

$169.00 Certificate Available
Duration & workload

7 weeks, 6-8 hours a week
Sessions

On-Demand
Level

Intermediate
Subtitles

English

Found in

Part of

Industrial Biotechnology and Industrial Fermentation

Overview

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This course provides the insights and tools for designing biotechnological processes with sustainability advantages, where choices of product and feedstock determine the specific process requirements. As fossil-based fuels and raw materials contribute to climate change, the use of renewable feedstocks, materials and energy as an alternative is in full swing.

This transition is not a luxury, it is a necessity. We can use microorganisms to convert organic streams (‘waste’ or residues) and/or CO2 into biomaterials, chemicals, nutrition products and biofuels.

Eight experienced course leaders will unfold the basics of industrial biotechnology and how to apply these to the design of fermentation-based processes to produce a wide range of bioproducts. Throughout the course, you will be challenged to design your own biotechnological process and evaluate its performance and sustainability.

The course includes guest lectures from industry and universities. By following this course, you will be able to contribute up-to-date ideas in the biotechnology field.

Syllabus

Getting started/Introduction is included in Week 1

Week 1. Biotechnology for Biobased Products

• Why develop a biobased/circular economy?

• Industrial biotechnology

• Feedstocks - renewable sources of biomass/CCU for biobased products

• Process to produce bio-PDO (1,3-Propanediol)

• Benefits for society and sustainability - evaluating the effects of biobased production

Week 2. Fermentation Essentials (PDO focus)

• Microbes and interaction with their environment

• Rates and balances

• The process reaction and the black box model

• The PDO case

• Introduction fermentation technology

• Scale-up via scale-down

Week 3. Downstream Processing Principles and Design

• Introduction to DownStream Processing (DSP)

• Seperating in stages

• Mechanical separations

• Molecular separations

• PDO Cases

Week 4. Integral, Zero-emission Bioprocess Design

• Towards an integrated bioprocess

• 1st and 2nd generation feedstock and pre-treatment: producing high quality feedstock

• 3rd to 5th generation feedstock: Alternative carbon, electron and energy sources

• Bioprocesses using 3rd to 5th generation feedstock

• Overall process - syngas fermentation to ethanol

Week 5. Process Design and Sustainability Assessment

• Conceptual process design

• Mass and energy balances

• Process economics

• Environmental impacts analysis and life cycle assessment

• Social sustainability

• Sustainability in a global context

Week 6. Wrap-up

• Closing lecture: Industrial Biotechnology outlook (preliminary title)

• Final assessment

Reviews

4.3 rating, based on 10 Class Central reviews

4.7 rating at edX based on 10 ratings

Start your review of Industrial Biotechnology

Malena Amézquita

This MOOC is perfect for people that want to become better fermentation scientists/engineers. It was so captivating and interesting that it motivated me to keep the pace throughout the course. By the time it was over, I felt really motivated beca…

This MOOC is perfect for people that want to become better fermentation scientists/engineers.

It was so captivating and interesting that it motivated me to keep the pace throughout the course. By the time it was over, I felt really motivated because I had a much stronger knowledge about biotechnology, and I was ready to implement new ideas at work.

I really liked the course structure and its consistency. I knew what to expect and I could plan my week accordingly. I started the MOOC with well-defined expectations of what I would learn and all of them were not only met but exceeded by the end.

I was pleasantly surprised when the teachers took less than a day to answer my questions—which was something I had never experienced before in any other MOOC. This definitely energized the class and made us participate more.

I would recommend this MOOC to anybody that’s looking to complement their career in biotechnology by understanding the technical aspects of the industry.
Anonymous

Industrial Biotechnology MOOC from TU Delft is a well-planned course focussing on the theoretical and application aspects of Bioprocess/Biochemical engineering. The course proved highly beneficial for me as it helped to refresh some of the basic con…

Industrial Biotechnology MOOC from TU Delft is a well-planned course focussing on the theoretical and application aspects of Bioprocess/Biochemical engineering. The course proved highly beneficial for me as it helped to refresh some of the basic concepts. Furthermore, some advanced concepts were broken down strategically to make them easy to understand. Bioprocesses, which are often considered black-boxes due to complicated operations, were made easy to understand. Besides the theoretical coursework, the MOOC introduces the real-world applications of the concepts taught and has several industrial examples. The sessions with experts from various industries were insightful as they revealed an in-depth technical perspective. Finally, during the course work, the organizers' support was beneficial, which kept me motivated to complete the course.
Anonymous

This is a first-class top-quality course given by experts in the field of industrial biotechnology and bioprocess engineering. As a chemical engineer I really enriched myself with the content of the course which was lacking in my previous formation. I really appreciate the fact that this course is available on-line and for free from one of the best and most well-known universities out there.

All in all, it is quite challenging and time consuming, with many exercises to fulfill and learn, but all the content is well posed and it enlarges the vision about bioreactors and bioprocess design. I strongly recommend this course to any chemical/process engineer student or professional working on this field.
Anonymous

Very complete MOOC that goes deep into Bioreactor design, from engineering the air requirements to calculating the economic and environmental impacts of a bioprocess. The level was challenging, so I had to spend some good amount of time on solving the exercises. All in all, really worth the money, as you get very fitting practice exercises and in general a lot more out of the course.

The instructors were always clear, and the forum was generally quite quick. So I recommend this course for anyone who is perhaps a Master student, who wants to catch up on Bioprocess Engineering, as it helped me tremendously.
Ronaldo Rodrigues

This online course was very important for my professional development. I was hired to work as a researcher in a Biotechnology Lab (my background was in the traditional chemical industry). It was essential for me to obtain such precise knowledge in MOOC Industrial Biotechnology offered by TU Delft. The content was dense and very well organized; teachers explore the themes logically and progressively; the presentation of lectures is attractive, and the extra-activities are challenging. A must-see for all people interested in Industrial Biotechnology. Highly recommended.

Ronaldo Rodrigues/National Institute of Technology/Brazil
Edgar Sebastian Gomez Hinostroza

I found this course utterly amazing, as it covers a wide range of topics, from the basics to a complete design of a biosynthetic process. Even when there were complex topics such as metabolic flux analysis, I could understand everything thanks to excellent lecturers with plenty of years of experience in their fields. Both examples and exercises are challenging, thus allowing us to understand real-life conditions. I consider this course an excellent complement to my formal training as a biotechnology engineer.
Benjamin Honorio

The best course I ever took about industrial biotechnology online. So challenging and with a case study that makes you go all the way from studying bacteria phisiology to the large scale production of a bioproduct. All with the pace of the best researchers in the field of biotechnology. Full of examples and excercises. If you work with bacteria, you better enroll on it. It will broaden your view about this fascinating subject.
Anonymous

Excellent course to discover or refresh the fundamentals of bioprocess engineering! The time commitment was accurate, the content was challenging but accessible. The lecturers were responsive and helpful.
Tareq Abdulaziz Abdullah RAWEH
Patrick E.