Learn about microbial coevolution and ecological phase transitions in this biology seminar presentation that explores iron resource dynamics among microbes. Delve into the Pseudomonas model system to understand siderophore-mediated interactions, examining the relationships between producers, cheaters, and various survival strategies. Explore the lock-key mechanisms between siderophore synthetase and receptors, with particular focus on single-receptor producers. Discover coevolution mining techniques for iron-related interactions, supported by experimental validation and predictive modeling. Examine the forces shaping microbial communities through agent-based metapopulation models and investigate how microbes actively explore resource dimensions. Understand the conditions necessary for stable coexistence between sneaky producers and the role of cheating in microbial communities through a generalized "resource partition" model.
Game of Iron: Mining Microbial Coevolution for Ecological Phase Transitions
BPPB Seminar via YouTube
Overview
Syllabus
Intro
Iron is one of the limiting resources fo microbes
Pseudomonas: A model system for diverse siderophore-mediated interacti
From sequence to strategy: producers, cheaters, and strategies in between
Lock-key relationship between siderophore synthetase and receptors
Single-receptor producers: clear Lock- Key pair between Rec and Syn
Method: Mining coevolution for the iron-n
Experimental validation of the interactio prediction methods Sequenced and predicted iron
Model the evolution: two forces shapin the community Agent-based metapopulation model
Life finds a way: microbes actively exp the resource dimensions
A generalized "resource partition" model
Conditions for stable coexistence betwee sneaky producers
Ongoing: role of "cheating" in the community
Taught by
BPPB Seminar
