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Explore the groundbreaking research of clinical neuroscientist Jill Goldstein in this 15-minute TED talk on the impact of sex differences in heart and brain disorders. Discover how prenatal stress and other factors affect males and females differently, influencing the development of major depression and cardiovascular disease later in life. Learn about the Women, Heart and Brain Global Initiative and its mission to understand the sex-specific origins of these major health issues. Gain insights into how the fetal environment shapes disease onset, expression, and treatment responses in adulthood, highlighting the importance of considering sex differences in medical research and treatment approaches.