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Explore advances in biomedical simulation of the human hand in this comprehensive lecture by Professor Wendy Murray from Northwestern University. Delve into the development of biomechanical models of the upper limb, focusing on the groundbreaking full musculoskeletal model of the hand and wrist. Learn about the anatomical, physiological, and technological factors considered in assembling the current model, which enables muscle-driven, forward-dynamics simulations of functional tasks involving coordinated kinematic and kinetic components for the whole hand. Discover the model's capabilities and current applications in fields such as basic motor control, exoskeleton and prosthetic design, rehabilitation for spinal cord injury and stroke patients, orthopaedic interventions, and injury prevention in sports. Gain insights into Dr. Murray's extensive research and its broad impact on understanding and improving function of the disabled upper limb.