Overview
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Explore the fascinating world of genetic mutations in this 35-minute lecture by Alison Woollard, a University Lecturer in Genetics at the University of Oxford. Delve into the fundamental concepts of DNA, genetic diversity, and evolution, starting with an examination of what mutations are and how they occur. Learn about the structure of DNA molecules, the process of DNA replication, and the various ways mutations can arise and affect cells. Discover the historical context of genetic research, including the contributions of Mendel and Darwin, and understand how natural selection drives evolutionary processes. Examine the significance of genome sequencing and its impact on various fields of biology. Consider the medical benefits and ethical implications of genetic testing and technologies like CRISPR. Conclude by pondering what makes humans unique from a genetic perspective, gaining a comprehensive understanding of how mutations shape life on Earth.
Syllabus
Introduction
Are there any mutants
What about the dogs
What does a mutation mean
The DNA molecule
How much DNA do we make
How does a mutation arise
How does a mutation change a cell
Fruit fly example
Mutations
Mendel
Charles Darwin
Natural Selection
Modification
Evolution
Nothing in Biology Makes Sense
Darwins Tree of Life
Darwins Tree
DNA
Fred Sanger
Whole Genomes
Typing
Genome Sequence
Fields of Biology
Medical Benefits
Genetics
Genetic Tests
CRISPR
Public Debate
What makes humans special
What makes humans unique
Taught by
The Royal Institution