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Explore strategies for building WebAssembly-first architectures at enterprise scale in this 33-minute conference talk by Sean Isom, former Adobe executive. Gain insights into the explosive growth of Wasm on the backend, including managed platforms, tooling, and WASI standardization. Compare Wasm to other runtime technologies like Kubernetes, FaaS, micro VMs, and eBPF. Learn how to leverage the Wasm component model across the stack for maximum portability and impact. Discover approaches to create flexible applications that evolve easily by utilizing the right technologies for specific use cases, ultimately leading to more robust solutions and improved developer experiences.