Veno-Occlusive Disease by Steven Margossian for OPENPediatrics

Explore a comprehensive 24-minute video lecture on veno-occlusive disease (VOD) after hematopoietic stem cell transplantation. Learn about the definition, pathophysiology, diagnosis, prevention, and management of VOD from Dr. Steven Margossian. Gain insights into clinical presentation, risk factors, diagnostic criteria, and ultrasound findings. Discover preventive measures and management strategies, including fluid and electrolyte management, renal and pulmonary support, and interventional measures such as defibrotide and transjugular intrahepatic portosystemic shunt (TIPS). Understand the classification of VOD and its implications for patient care. This educational content is part of OPENPediatrics, an interactive digital learning platform sponsored by Boston Children's Hospital, offering peer-reviewed, open-access resources for healthcare clinicians worldwide caring for critically ill children.