Overview
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Explore the challenges and solutions in somatic NGS analysis and literature review for clinical oncology applications in this 50-minute webinar presented by Chelsea Alexander, MS, CGC, and Dr. Aarthi Goverdhan from QIAGEN Digital Insights. Learn about the Human Somatic Mutation Database (HSMD), a new expert-curated resource that streamlines variant interpretation, literature curation, and clinical trial matching. Discover how this comprehensive database, containing data from over 419,000 real-world clinical oncology cases, can reduce literature review time by up to 90%. Gain insights into gene-level, alteration-level, and disease-level information, as well as clinically observed variant frequencies across diseases. Understand how to leverage HSMD's features, including the Gene Explorer, Alterations Table, Drug Section, and Clinical Trials information, to enhance tumor genomic profiling and decision-making at point-of-care. Address the challenges of distinguishing between somatic and germline variants, and learn about commercial tumor profiling tests and professional interpretation services. Participate in a Q&A session to further explore the application of HSMD in clinical oncology practice.
Syllabus
Introduction
Challenges faced by genetic counselors
The evolution of tumor genomic profiling
How much time do genetic counselors spend on one patient
What is Human Somatic Mutation Database
Human Somatic Mutation Database Homepage
Gene Explorer
Gene Page
Alterations Table
Drug Section
Clinical Trials
Tumor Only Testing
commercial tumor profiling tests
lab agnostic
professional interpretation service
genetic counselors
somatic vs germline variants
Alteration Explorer
QA Session
Taught by
Labroots