Unveiling Insights: Leveraging Single-Cell Transcriptomics and Epigenomics for Biomarker Discovery

Explore cutting-edge single-cell genomics techniques for biomarker discovery in this 57-minute webinar presented by Dr. Derek Janssens and Dr. Ilaria Iacobucci. Delve into the applications of single-cell transcriptomics and epigenomics in understanding biological processes such as tumorigenesis, cell development, and differentiation. Learn how these methodologies can be utilized to identify crucial biomarkers, including gene fusions, splicing isoforms, and cell type-specific histone modification patterns. Dr. Janssens, a postdoctoral researcher at Fred Hutchinson Cancer Center, shares insights on developing novel chromatin profiling tools and optimizing CUT&Tag for single-cell applications. Dr. Iacobucci, a Principal Scientist at St. Jude Children's Research Hospital, discusses her research on high-risk myeloid and lymphoid leukemia subtypes, focusing on identifying genetic alterations with diagnostic, prognostic, and therapeutic relevance. Gain valuable knowledge from these experts as they showcase the power of single-cell genomics in advancing our understanding of complex biological systems and its potential for groundbreaking discoveries in cancer research and beyond.