Overview
Syllabus
Intro
Overview of Talk
Cancer Microenvironment, immune cells influence tumor progression, drug response
Many cell types
Exploratory data analysis (EDA)
Single Cell Data Analysis Pipeline
Classical Dimension Reduction Matrix Factorization approaches
Eigenvalues
Considerations when applying PCA
Correspondence Analysis
Multidimensional scaling (MDS)
Tensor Integration of 5 data sets (NC160) using multi-CIA
Reduce features to "groups of genes" to score get groups feature level single per case (moGSA)
Application of moGSA to finding PanCancer Immune subtypes
Correlation between 16 Clusters, leucocyte fraction and mutation load
Summary: multiple dataset integration
ENCODE
Taught by
Open Data Science