Type 2 Hypersensitivity Reactions - Antibody-Mediated Cytotoxic Hypersensitivity

Explore the mechanisms and implications of Type 2 Hypersensitivity Reactions, also known as immediate allergic reactions, in this comprehensive 38-minute lecture. Delve into the role of immunoglobulin G (IgG) and IgM antibodies in targeting antigens on cells or extracellular materials, leading to cytotoxic processes involving the complement system. Understand how these reactions can interfere with normal cellular operations, causing stimulatory or inhibitory dysfunction. Learn about intrinsic and extrinsic antigens that can trigger these reactions, including blood products and medications. Discover diagnostic approaches, from laboratory tests to invasive procedures, and explore management strategies ranging from supportive care to antibiotics, immunosuppressive medications, and surgery.