Tuberculosis - Research Towards Eradication

Explore the ongoing battle against tuberculosis in this 17-minute TEDx talk by Dr. Jonathan Shanahan, a postdoctoral medical research associate at Cambridge University. Delve into the current global impact of tuberculosis and the cutting-edge research being conducted at labs like the Ramakrishnan lab at the University of Cambridge. Learn about Dr. Shanahan's focus on two crucial virulence factors essential for the bacteria to cause disease, and his efforts to understand how these proteins establish infection. Gain insights into the work of the Ramakrishnan Research Group, including their study of mycobacterium ESX-1 and advanced therapies for TB. Discover the latest developments in understanding ESX-1-mediated virulence in early infection phases, macrophage phagosomal damage, granuloma formation, and overall virulence. This talk, delivered at TEDxThe Perse School Cambridge, offers a glimpse into the ongoing research aimed at eradicating one of the world's most persistent diseases.