The Structure, Function, and Evolution of Human Chromosome 8

Explore the groundbreaking research on human chromosome 8 in this 24-minute webinar presented by Dr. Glennis Logsdon, a postdoctoral research fellow at the University of Washington. Delve into the first complete telomere-to-telomere assembly of a human autosome and discover how it resolves long-standing gaps in our understanding of chromosome structure. Learn about the 2.08 Mbp centromeric α-satellite array, the 644 kbp β-defensin copy number polymorphism linked to disease risk, and the 863 kbp variable number tandem repeat that can function as a neocentromere. Gain insights into the evolution of chromosome 8's centromere over the past 25 million years through the use of advanced long-read sequencing technologies and assembly methods. After watching, registered Labroots members can earn PACE credits by following the provided instructions.