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Explore a 38-minute conference talk that delves into how recent hardware advancements are revolutionizing cloud computing design and architecture. Learn how the traditional hardware limitations of slow storage, high CPU costs, and expensive networking have been transformed with the emergence of new technologies. Discover the shift from magnetic storage obsolescence to high core count CPUs, faster networking infrastructure, and the mainstream adoption of GPUs and smart NICs. Examine the new design challenges that have emerged, including unexpected bottlenecks and the complex balance between hardware design, cloud scalability, application resilience, and storage optimization. Gain practical insights into designing both large and small OpenStack clouds, implementing software-defined storage, and managing latency-sensitive cloud workloads. Master budget-conscious design strategies to maximize resources and evaluate the trade-offs between greenfield deployments and hardware reuse in terms of total cost of ownership and risk assessment. Presented by Christian Huebner at the OpenInfra Foundation, this talk provides valuable perspectives for cloud architects and IT professionals navigating the evolving hardware landscape.