The Evolution of Gene Expression - From Microevolution to Major Transitions
Harvard University via YouTube
Overview
Syllabus
Intro
Puzzle in modern biology
Microevolution
Macroevolution
Evolutionary theory
Biodiversity
Questions
Major transitions: groups
Major transitions: Energy
Major transitions: Genetic systems
History
Prokaryotes/Eukaryotes
Eukaryotes reproduction
Eukaryotes transcription initiation
Trans and cis-regulation
Dominance
Genetic load
Diploidy
The selfish gene
Metaphor #1
Metaphor #2
Metaphor #3
Summary part 1
Diploid expression
Expression to fitness
Fixation stronger cis-regulator
Cis-regulator runaway
"Strength" ?
Level of Expression
Coevolution of regulators
Cis-cis coevolution
Summary part II
A theory
Regulatory region evolution
Regulation & Modern synthesis
Taught by
Harvard University