Overview
Discover the groundbreaking advancements in cell programming and their potential to revolutionize medicine and technology in this enlightening talk by neurosurgeon and stem cell biologist Mark Kotter. Explore the latest breakthroughs in reprogramming cells at the genetic level, learning how scientists are gaining unprecedented control over cellular mechanisms. Delve into the collaborative efforts across biology, computer science, physics, and mathematics that are driving this biological revolution. Gain insights into the promising applications of cell programming, including extended lifespans, cures for debilitating ailments, and the birth of new technologies. Understand the importance of robust activation of cell type programs and how it challenges existing theories on cell reprogramming. Follow Dr. Kotter's journey from discovering the role of macrophages in brain regeneration to developing the opti-ox gene targeting approach. Learn about ongoing research in areas such as Alzheimer's treatment and cell therapies, and envision the future possibilities of this transformative field.
Syllabus
Intro
Last wave of innovation
Gene regulatory networks
Programming biology
Programming maths
Engineering biology
Programming higher species
Selfmade choices
The new paradigm
Can this paradigm be generalized
Mark Kotters lab
Number of experiments required
Refinement of experimental approach
How is the cell type determined
Harald Weintraub
Human Cell Atlas
Liver cells
Whats next
Leading innovators
Alzheimers
Cell therapies
Future applications
Taught by
The Royal Institution