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Explore the intricate relationship between Python and Rust in this 44-minute PyCon US talk. Delve into the mechanics of how Python function calls execute Rust code via PyO3, a powerful Rust library for language binding. Gain insights into the benefits of integrating Rust into your Python stack and follow a step-by-step breakdown of the Python interpreter and PyO3's internal processes. Learn about the stages of "native" function calls, applicable to various languages including Python standard library "builtins", Cython, and C++/pybind11. While technical in nature, the talk assumes no prior Rust knowledge, making it accessible to those with a basic understanding of Python functions and types. Witness illustrative examples of Rust and C code, thoroughly explained and dissected. Access accompanying slides for a comprehensive learning experience.