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Explore the advantages and potential pitfalls of GraphQL compared to traditional REST APIs in this 37-minute PyCon US talk. Learn how to leverage data-loaders, async/await, dynamic query generation, and other performance optimizations to create a flexible, performant interface for front-end services. Discover techniques to address the n+1 query problem and navigate GraphQL's idiosyncrasies. Dive into topics such as query language, schema design, database integration with SQL Alchemy, and GraphQL libraries. Gain insights on latency management, Python implementation, and the mathematics behind GraphQL operations. Witness a live demo showcasing best practices and learn when to use GraphQL effectively. Conclude with a discussion on query counters and information about GraphQL meetups.