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Explore the concept of isomorphic JavaScript applications in this conference talk from JSConf 2014. Discover how Airbnb tackled challenges with single-page apps by developing a shared UI layer and reusable business logic that runs on both client and server. Learn about the evolution of their approach, from converting a Backbone app to run on Node.js and Express, to the creation of the open-source Rendr library. Gain insights into various "isomorphic" approaches, ranging from sharing minimal modules to entire application code. Understand the trade-offs between code sharing and the complexity of bridging browser and server environments. Delve into real-world examples, common application patterns, and open-source tools for building isomorphic apps, including Handlebars, Superagent, Browserify, and Esprima.