Making, Breaking and Linking Memories in Mice

Explore groundbreaking neuroscience research on memory formation and processing in a 43-minute lecture delivered by Dr. Sheena Josselyn, a distinguished Senior Scientist at The Hospital for Sick Children and Professor at the University of Toronto. Delve into fundamental questions about how the brain encodes, stores, and utilizes information through studies conducted on mice, with implications for understanding human neurological conditions ranging from autism spectrum disorder to PTSD and Alzheimer's disease. Learn about the concept of 'engrams' - physical brain changes that encode memories - and discover how specific neurons are recruited to form these memory traces across multiple levels including epigenetic, synaptic, and cell assembly. Gain insights into cutting-edge research examining how neuronal membership in memory engrams may evolve over time or through new experiences, contributing to both basic understanding of brain function and potential therapeutic strategies for various neurological disorders.