Selective Neuronal Vulnerability in Neurodegeneration

Explore selective neuronal vulnerability in neurodegeneration through this 28-minute webinar presented by Dr. Marija Cvetanovic, Associate Professor at the University of Minnesota. Delve into the cellular and molecular pathways underlying neurodegenerative disorders, with a focus on Spinocerebellar Ataxia type 1 (SCA1). Discover how pre-existing physiological differences in neurons and surrounding glia may contribute to selective vulnerability in brain regions. Learn about the non-uniform degeneration of the cerebellum in SCA1 mice, mirroring patterns seen in human patients. Gain insights from cutting-edge research employing mouse and viral genetics, cell and molecular biology techniques, mouse behavior, fiber photometry, transcriptomics, and disease modeling with induced pluripotent stem cells. Earn PACE credits by watching the webinar and following the provided instructions.