Petascale Connectomics and Beyond - IPAM at UCLA
Institute for Pure & Applied Mathematics (IPAM) via YouTube
Overview
Syllabus
Intro
Serial section electron microscopy (EM)
EM image dataset from fruit fly brain
Software stack for petascale connectomics
Completion of Drosophila connectome expected 2023
What can we do with connectomes?
What can a computer scientist do with connectomes?
Graph reduction: 50,000 fly neurons→ 28 clusters
Example cluster: ellipsoid body (important in navigation)
Artificial neural networks
Brains
NIH BRAIN CONNECTS (beginning 2023)
Competing proposals for exascale connectomics
Serial section tilt series tomography
Why is this challenging?
Tomography with convolutional nets
Tomography with 5 dual axis simulated tilts
Image reconstruction from 5 dual axis simulated tilts
How to generate ground truth from real data?
New implementation of iterative reconstruction
Application to mouse retina
Plan for handling real images
Technological revolution driven by imaging + computing
Taught by
Institute for Pure & Applied Mathematics (IPAM)