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Explore the evolution of scleroderma clinical treatment trials in this 57-minute conference talk by Dr. Maureen Mayes at the 2023 National Scleroderma Conference. Gain insights into past successes and failures in treatment trials, understand the typical trial types required for FDA approval, and learn about the roles of various sponsors in trial design and execution. Discover the mandated oversight processes ensuring participant safety and result reliability. Understand the qualification criteria for trial participation, including inclusion and exclusion factors. Evaluate whether participating in a clinical trial might be appropriate for your situation. Delve into the past, present, and future landscape of scleroderma research to better comprehend the advancements and challenges in this field.