Renin Angiotensin Aldosterone System (RAAS) - Mechanisms and Functions

Explore the Renin Angiotensin Aldosterone System (RAAS) in this comprehensive 59-minute lecture. Delve into the intricate mechanisms of renin production, including the role of the juxtaglomerular apparatus and macula densa. Examine how low renal perfusion affects glomerular filtration and triggers renin release. Investigate the systemic mechanisms of renin production, including baroreceptor activation and sympathetic outflow. Understand the function of renin in converting angiotensinogen to angiotensin I, and the subsequent conversion to angiotensin II by ACE. Analyze the actions of angiotensin II on blood pressure regulation and aldosterone release. Learn about the effects of aldosterone and angiotensin II on the central nervous system. Conclude with an overview of the pathological functions of RAAS, providing a comprehensive understanding of this crucial physiological system.