Quantitative SPECT and Applications in Disease Characterization and Therapy Monitoring

Explore the principles and applications of Quantitative SPECT imaging in this comprehensive 29-minute lecture by Dr. Du from Johns Hopkins Medicine. Delve into topics such as two-camera SPECT/CT systems, imaging agents, and gamma camera technology. Examine analytical methods, effects of attenuation, scatter, and collimator-detector response on image quality. Learn about partial volume effects, statistical noise, and model-based compensation techniques for quantitative reconstruction. Discover practical applications in renal mass imaging, radiopharmaceutical therapy, and dosimetry. Investigate quantitative SPECT activity estimation, bone SPECT, and alpha emitter imaging. Gain insights into advanced techniques like model-based crosstalk compensation and simultaneous dual radionuclide reconstruction, enhancing your understanding of SPECT's role in disease characterization and therapy monitoring.