Penicillin - Mechanism of Action and Pharmacology

Explore the comprehensive pharmacology of penicillin and its mechanism of action in this extensive 3-hour 51-minute lecture. Delve into the history, discovery, and development of this groundbreaking antibiotic, from Alexander Fleming's initial discovery to its purification and clinical use. Learn about the various types of penicillins, their spectrum of activity, and their effectiveness against different bacterial infections. Understand the beta-lactam antibiotic class, how penicillin works to combat bacterial infections, and its limitations against viral infections. Examine the prevalence and management of penicillin allergies, as well as cross-reactivity with other antibiotics. Gain insights into semisynthetic penicillins and their broader spectrum of activity. This in-depth lecture provides essential knowledge for medical students, healthcare professionals, and anyone interested in understanding the role of penicillin in modern medicine.