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Explore the cutting-edge developments in neurotechnology and human augmentation in this opening keynote address from the ACM Interactive Surfaces and Spaces Conference. Delve into the impact of Artificial Intelligence on brain-computer interfaces (BCI) and neurotechnologies. Discover how recent advancements in brain activity measurement, neuroimaging analysis, and understanding of brain processes are opening new avenues for transdisciplinary applications. Learn about the identification of brain activity "fingerprints" and their potential uses in linking mental states, improving neuropsychiatric diagnostics, enhancing BCI reliability, optimizing brain processes through neurofeedback, and developing neuromodulation-based therapies. Examine the progress in understanding abstract cognition and its parallels to physical space exploration. Consider the implications of these neurocognitive technologies on human-computer interaction and their potential to fundamentally alter human nature, social interactions, and our relationship with the physical environment.