Overview
Explore non-IgE mediated hypersensitivity drug reactions in this comprehensive physician grand rounds presentation. Delve into various types of drug reactions, their prevalence, and specific syndromes like drug hypersensitivity syndrome. Examine the role of pharmacogenomics in reactions to drugs such as allopurinol and carbamazepine. Learn to differentiate between conditions like erythema multiforme, Stevens-Johnson Syndrome, and hypersensitivity vasculitis. Discover causes and management strategies for drug-induced photosensitivity and allergic interstitial nephritis. Gain insights into prognosis and treatment options, including the use of cyclosporine and acetylcysteine. Enhance your understanding of these complex reactions to improve patient care and outcomes.
Syllabus
Welcome
Introduction
Types of drug reactions
Data on drug reactions
Drughypersensitivity syndrome
What drugs caused it
Pharmacogenomics
Allopurinol Carbamazepine
Tegretol
Other Drugs
Whats Caught
General Mobility
erythema multiforme
EMM
Stevens Johnson Syndrome
Differentiation
Hypersensitivity Vasculitis
Photosensitive drug reactions
Causes of a GP
What to do
Skorton Score
Cyclosporine
Acetylcysteine
Allergic interstitial nephritis
Proton pump inhibitors
Prognosis
Recap
Questions
Taught by
Mary Greeley Medical Center