Myasthenia Gravis vs Lambert-Eaton Myasthenic Syndrome - A Neurological Comparison

Learn about two significant neuromuscular disorders in this comprehensive medical video that compares Myasthenia Gravis (MG) and Lambert-Eaton Myasthenic Syndrome (LEMS). Explore the distinct characteristics of these autoimmune diseases, including their underlying mechanisms, where MG involves anti-acetylcholine receptor antibodies targeting nicotinic receptors at the neuromuscular junction, while LEMS features autoantibodies against presynaptic voltage-gated calcium channels. Understand the key differences in symptoms, with both conditions causing muscle weakness and fatigue but presenting unique patterns of involvement in skeletal muscles, extraocular muscles, and autonomic systems. Discover the diagnostic approaches, treatment options, and the important connection between LEMS and paraneoplastic syndrome, particularly its association with small cell lung cancer.