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Explore the critical accessibility challenges in client-side MVC frameworks like Angular, Ember, React, Backbone, and Spine in this JSConf EU 2014 talk. Discover proposed solutions to make web applications more inclusive, focusing on keyboard accessibility and assistive technology compatibility. Learn about essential techniques such as focus management, ARIA live regions, and JavaScript testing to ensure your apps are usable by everyone. Gain valuable insights into creating more accessible JavaScript-based applications, helping to bridge the gap between modern web development and universal usability.