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Explore the evolution of NATS as a reactive substrate in this 28-minute keynote address delivered by Byron Ruth, Director of Developer Relations at Synadia. Delve into the core functionality of NATS as a stateless message broker and its decade-long reliability. Learn about the recent introduction of JetStream, a persistence subsystem for NATS, and discover how it enhances the platform's capabilities. Gain insights into the alignment of JetStream with reactive principles and patterns, and understand the potential impact on distributed systems development. Examine the innovations and advancements made in the past 18 months, and grasp the significance of these developments for the future of reactive programming and message-oriented middleware.