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Explore best practices for Site Reliability Engineers (SREs) supporting GPU-enabled Kubernetes clusters for High-Performance Computing (HPC) workloads in this informative conference talk. Delve into the unique challenges of operating GPU-equipped nodes, focusing on telemetry, observability, and criteria for human intervention. Learn about essential metrics SRE teams should incorporate into their operational tools to effectively support HPC and AI use cases, including Generative Pre-trained Transformers (GPTs), machine learning, and quantitative modeling. Examine a working example of custom plugin monitors for the Kubernetes node-problem-detector daemon, utilizing NVIDIA's open-source DCGM and NVML bindings. Gain insights into the operational importance of metrics exposed by NVIDIA's DCGM-Exporter to Prometheus for maintaining cluster and workload health. Enhance your ability to keep HPC running smoothly on Kubernetes with GPU support.