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Sensing Psychosis: Toward Robust Computational Phenotypes in Severe Mental Illness

Institute for Pure & Applied Mathematics (IPAM) via YouTube

Overview

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Explore a comprehensive lecture on computational psychiatry and its potential to revolutionize mental health care. Delve into the challenges of applying personalized medicine in psychiatry and learn how pervasive computing offers unprecedented opportunities to build dynamic models of mental illness. Discover how unobtrusive, quantitative behavioral phenotyping strategies can transform the understanding of causal relationships between illness fluctuations, contextual factors, and treatment interventions. Examine recent efforts to bridge complementary approaches through single-case experimental designs in individuals with severe mental illnesses such as bipolar disorder and schizophrenia. Gain insights into the methodology, including scales of data, simultaneous signals, motion sequencing, and state-space models, that contribute to developing robust computational phenotypes in severe mental illness.

Syllabus

Introduction
Framework
The Brain
Defining constructs
Recording encounters
Offtheshelf solution
Semistructured interview
Results
Interrogation
Vowel space ratio
Expressivity
Bipolar disorder
Multimodal approach
Backend
Methodology
Scales of Data
Day of Week
Sunday
Smoking
Simultaneous Signals
Motion Sequencing
Timecourse
Time resolution
Time synchronization
Transfer functions
Statespace models

Taught by

Institute for Pure & Applied Mathematics (IPAM)

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