Explore a comprehensive World Shared Practice Forum podcast featuring Drs. Suchitra Ranjit and Luregn Schlapbach as they discuss individualized hemodynamic support for pediatric patients with septic shock, with a focus on lower and middle-income countries. Learn about the challenges in early recognition of septic shock in children globally, understand the concepts of flow, pressure, and filling in septic shock, and discover an individualized approach to fluid use in treatment. Review current literature on fluid use in pediatric and adult patients, and gain insights into administering and assessing various therapies such as fluids, inotropes, and pressors. This 38-minute educational resource, produced by OPENPediatrics, offers valuable knowledge for healthcare professionals dealing with critically ill children in various resource settings.
Individualized Hemodynamic Support for Pediatric Patients with Septic Shock
Overview
Syllabus
• Fleischmann-Struzek C, Goldfarb DM, Schlattmann P, Schlapbach LJ, Reinhart K, Kissoon N. The global burden of paediatric and neonatal sepsis: a systematic review. Lancet Respir Med. 2018;63:223-230. doi:10.1016/S2213-26001830063-8
• Maitland K, Kiguli S, Opoka RO, et al. Mortality after fluid bolus in African children with severe infection. N Engl J Med. 2011;36426:2483-2495. doi:10.1056/NEJMoa1101549
• Gu W, Deng X, Lee M, et al. Rapid pathogen detection by metagenomic next-generation sequencing of infected body fluids. Nat Med. 2021;271:115-124. doi:10.1038/s41591-020-1105-z
• Meyhoff TS, Hjortrup PB, Wetterslev J, et al. Restriction of Intravenous Fluid in ICU Patients with Septic Shock. N Engl J Med. 2022;38626:2459-2470. doi:10.1056/NEJMoa2202707
• National Heart, Lung, and Blood Institute Prevention and Early Treatment of Acute Lung Injury Clinical Trials Network, Shapiro NI, Douglas IS, et al. Early Restrictive or Liberal Fluid Management for Sepsis-Induced Hypotension. N Engl J Med. 2023;3886:499-510. doi:10.1056/NEJMoa2212663
Taught by
OPENPediatrics
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