Base-Edited CAR-T Cell Therapy for Incurable Leukemia - A Breakthrough Case Study

Learn about a groundbreaking medical case through this 33-minute medical lecture exploring how a teenage girl's incurable leukemia was successfully treated using base-edited CAR-T cell intervention. Examine the revolutionary technology behind this medical breakthrough, following the case of Alyssa who showed no signs of cancer six months after receiving this innovative treatment. Delve into the technical aspects of base editing in genomic DNA, understand the role of CAR T-cells in cancer treatment, and explore the implications of this advancement for treating terminal blood cancers. Gain insights into the mechanisms of T-cell leukemia, the function of CD7 and CD19 markers, and the evolution of immunotherapy approaches in cancer treatment.