Hypocomplementemia - Low Plasma Complement Level

Explore the intricacies of hypocomplementemia, or low plasma complement level, in this 15-minute educational video. Delve into the causes of this condition, including underproduction and over-destruction of complement proteins. Learn about its association with various diseases, particularly systemic lupus erythematosus (SLE), where low levels of C3 and C4 complement proteins are commonly observed. Gain insights into the classical complement pathway and its significance in immune function. Compare this information with the alternative complement pathway, which is briefly mentioned in relation to paroxysmal nocturnal hemoglobinuria. Enhance your understanding of this important aspect of immunology and its clinical implications in various medical conditions.