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How to Clone a Mammoth - The Science of De-Extinction - With Beth Shapiro

The Royal Institution via YouTube

Overview

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Explore the fascinating science of de-extinction in this 54-minute lecture by evolutionary biologist Beth Shapiro. Delve into the controversial process of bringing extinct species back to life, from selecting candidates for resurrection to sequencing genomes and managing revived populations. Learn about ancient DNA research, genetic diversity, and cutting-edge techniques like CRISPR-Cas9. Examine the feasibility and ethical implications of resurrecting mammoths, passenger pigeons, and other extinct animals. Discuss the potential ecological impacts of de-extinction projects and their role in conservation efforts. Consider the challenges of recreating extinct species beyond just their genomes, including differences in appearance and behavior. Gain insights into ongoing de-extinction initiatives and their potential to impact ecosystems, such as the role of herbivores in climate change mitigation.

Syllabus

Intro
Climate change
Rapid global warming
Ancient DNA
Genetic Diversity
DeExtinction
Mammoths
Somatic Cell Nuclear Transfer
WellPreserved Mammoths
Mammoth Genomes
Human Genome
Shotgun Sequencing
Mammoth Sequencing
Plan C
CRISPR Caste 9
What should we target
What else
Whats next
Feasibility of Phase 2
Stellers Sea Cow
We are much more than genomes
Differences in appearance
Mammoth deextinction
Deextinction projects
Ecological reasons
Impact of herbivores
Impact of elephants
Black footed ferrets

Taught by

The Royal Institution

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