Heteroresistance: Mechanisms, Diagnosis and Clinical Implications

Explore the complex phenomenon of heteroresistance in bacteria through this 43-minute video lecture presented by the American Society for Microbiology. Delve into the mechanistic basis of heteroresistance, distinguishing it from related concepts like persistence and tolerance. Learn from experts Dr. David Weiss and Dr. William Miller as they discuss the differences between these phenomena, examine the underlying mechanisms in both Gram-positive and Gram-negative bacteria, and explore the clinical implications and diagnostic approaches for heteroresistance. Gain insights into how understanding heteroresistance may impact the deployment of antibacterials in clinical practice. Discover recent research on cefiderocol heteroresistance in Pseudomonas aeruginosa and access additional resources for further study in antimicrobial resistance.