Overview
Watch a 29-minute seminar presentation from the Biological Physics/Physical Biology series where Gabor Balazsi explores the complex fitness landscapes of cancer. Delve into key topics including evolution, protein distribution, drug mechanisms, and synthetic biology approaches to understanding cancer. Learn about metastasis regulation, invasion processes, and experimental validation methods. Examine the relationship between mean responses and noise in cancer systems, while gaining insights into nonmonotone responses and their underlying mechanisms. The presentation concludes with an interactive Q&A session, offering deeper understanding of the intersection between physics and cancer biology.
Syllabus
Intro
Evolution
Fitness landscapes
Protein distribution
How do drugs work
Synthetic biology
Metastasis
Regulation of metastasis
How to check metastasis
Invasion
Results
Validation
Orthod process
Experimental results
Main message
Mechanism
Nonmonotone response
Questions
Mean and noise
Taught by
BPPB Seminar