Explore a 29-minute webinar presented by Dr. Mark Dürkop, an expert in biopharmaceutical process development with over 10 years of experience. Delve into the world of advanced process modeling for bioprocess development and manufacturing, examining the importance of experiments, data, hybrid models, and digital twins. Discover success stories from both upstream and downstream processes that highlight the benefits of using these advanced modeling techniques. Learn about the essential components needed for accurate process description and knowledge transfer from early-stage development to manufacturing. Gain insights into hybrid modeling, model-based process optimization, fast process characterization, scale-up modeling, soft sensors, and ideal TFF process conditions. Conclude with a demonstration of the Hybrid Modeling Toolbox and earn PACE credits upon completion.
From Experiments to Digital Twins: Advanced Process Modeling in Biopharmaceutical Development
Overview
Syllabus
Intro
What do we need for better bioprocesses?
Circle of process modeling
Hybrid Modeling (high level view)
Why is Hybrid Modeling superior?
Model-based process optimization
Fast process characterization (iDOE)
Fast characterization with iDoE
Scale-up Modeling
Soft sensor
Ideal TFF Process conditions
TFF flux prediction
Continuous TFF prediction
Diafiltration (Test Data)
Summary
Hybrid Modeling Toolbox Demonstration
Taught by
Labroots
