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Explore the intricacies of the adrenal gland's zona fasciculata and its primary hormone, cortisol, in this comprehensive 29-minute lecture video. Delve into the third installment of a four-part series on the adrenal gland, presented by Professor Zach Murphy. Gain in-depth knowledge about the structure and function of the zona fasciculata, the biosynthesis of cortisol, and its crucial role in the body's stress response and metabolic regulation. Understand the physiological effects of cortisol on various organ systems, including its impact on glucose metabolism, immune function, and cardiovascular health. Learn about the regulation of cortisol secretion through the hypothalamic-pituitary-adrenal (HPA) axis and the importance of maintaining proper cortisol levels for overall well-being. This educational video is part of the Ninja Nerd endocrinology series, offering a thorough examination of this essential adrenal hormone.