Explore the complex relationship between genetics, appetite control, and obesity in this 58-minute lecture by geneticist and neuroscientist Giles Yeo from The Royal Institution. Delve into the biological variations in appetite control and how genetics can be used as a tool to understand them. Learn about the obesity epidemic, its contemporary causes, and the role of genetic makeup in determining why some individuals eat more than others. Discover insights on topics such as leptin, monogenic obesity, mutations, risk scores, and the concept of genetics as a "hand of cards." Gain a deeper understanding of how genes influence body weight and appetite, and explore the interplay between genetic predisposition and lifestyle factors in the development of obesity.
Overview
Syllabus
Intro
Genetics as an excuse
Avoid becoming food
The 7 deadly sins
The second law of thermodynamics
Obesity is a problem
The data
Are your genes to blame
Why have we become obese
Leptin
Can a naturally occurring mutation make you fat
Can we do the same thing with leptin
How leptin works
Is leptin reversible
Is leptin a dog thing
Labradors
Food Motivation
Monogenic Obesity
Mutations
Monogenic Diseases
Where You Put Your Fat
Risk Score
Risk vs Predictability
Genetics as a Hand of Cards
The Desert Tummy
Taught by
The Royal Institution
