Diosgenin Induces Anti-Hyperalgesic Effect via Antagonism of Transient Receptor Potential Vanilloid 1 in Pain Model

Explore the anti-hyperalgesic effects of diosgenin in this 28-minute webinar presented by Dr. Md. Mahbubur Rahman, a veterinarian and biomedical researcher. Delve into the potential of diosgenin, a botanical steroidal saponin, as an antagonist of Transient Receptor Potential Vanilloid 1 (TRPV1) in pain models. Learn about the speaker's extensive background in veterinary medicine and his research on diosgenin's anti-nociceptive properties. Discover the methodology used in both in vivo mouse experiments and in vitro studies on dorsal root ganglion (DRG) and Chinese hamster ovary (CHO) cells to investigate the mechanism of diosgenin's anti-nociceptive effects. Gain insights into the role of TRPV1 in nociception and how diosgenin's antagonism of this receptor may contribute to pain relief.