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Explore the evolving landscape of 21st-century science in this thought-provoking 47-minute talk by David Krakauer from the Santa Fe Institute. Delve into the shift from reductionist approaches to complex systems science, examining how the traditional method of breaking things down into basic parts fails to explain emergent phenomena in life, intelligence, language, innovation, ecosystems, and economies. Discover how advancements in computer processing and the rise of machine intelligence have revolutionized data analysis and correlation. Learn about the impact of the Internet on scientific collaboration and resource sharing. Understand the need for a diverse, global community of thinkers to tackle the most challenging problems at the intersection of multiple scientific disciplines. Gain insights into the daring new adventure of discovery that requires abandoning comfortable categories and embracing a more holistic approach to understanding our world.