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Explore the transformative power of information in this thought-provoking lecture by David Krakauer, Director of Wisconsin Institute of Discovery. Delve into the roles of energy and information in 21st century biology as part of the C4 Public Lectures series. Discover fascinating concepts such as communicating with aliens, Shannon Hartley theorem, von Neumann's contributions, the Planck Bound, light cones, and the Handbook of Biological Data. Gain insights into the Enigma Machine and its significance. Join a panel discussion led by Steve Paulson following the lecture, featuring additional perspectives from Geoffrey West and Jessica Flack. Recorded on October 1, 2012, this 26-minute video offers a captivating exploration of information's impact on modern biology and beyond.