Shear-Induced Dynamics and Mechanical Responses in Biological Tissues

Explore the dynamic mechanical responses of biological tissues to shear forces in this 43-minute talk by Dapeng "Max" Bi, presented at the Erwin Schrödinger International Institute for Mathematics and Physics (ESI). Delve into computational models and theoretical frameworks examining shear-driven solidification in epithelial tissues, demonstrating the transition from fluid-like to solid-like states under strain. Investigate discontinuous shear thickening in tissue rheology, focusing on the interplay between external and internal stresses during morphogenesis. Analyze plastic response and avalanche dynamics in tissues under large deformations, revealing collective cell rearrangements in response to stress. Examine the mechanical properties of multilayered skin epidermis under shear, including transitions from ductile to brittle responses based on interfacial tensions and cellular configurations. Gain comprehensive insights into the mechanisms governing tissue mechanics, with implications for understanding developmental processes and designing bioengineered systems.