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Explore the time-domain perspective of quantum optics in this comprehensive lecture by Prof. Denis Seletskiy from femtoQ Lab at Polytechnique Montréal. Delve into the advantages of time-domain quantum optics for technological applications in quantum computing, communication, and sensing. Examine the experimental results of subcycle sampling of the variance of the amplitude quadrature of a bare vacuum state at mid-infrared frequencies. Learn about the potential for subcycle quantum state tomography and sampling of high-order statistical moments. Discover fundamental applications and gain insights into mid-infrared sensing technologies where subcycle quantum optics opens new opportunities. This colloquium, presented at the Centrum Fizyki Teoretycznej PAN, offers a fresh approach to understanding quantum optics beyond traditional frequency-domain descriptions.