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Explore the challenges and solutions of instrumenting managed runtime applications with eBPF in this informative conference talk. Delve into the complexities of using eBPF beyond the Linux Kernel and native applications, focusing on languages like Go and Java that compile to native code but are managed by runtimes. Discover approaches to instrumenting applications with non-standard symbol tables, dynamic code recompilation, and reference-moving memory managers. Learn from the speakers' experiences, including successes and failures, in applying eBPF to natively compiled applications running with managed runtimes. Gain valuable insights into overcoming obstacles such as dynamic symbol tables, garbage collection, and stack size fluctuations between 'uprobe' and 'uretprobe' operations.