Explore a groundbreaking TED talk by genomics pioneer Craig Venter as he shares insights from his global expedition to map ocean biodiversity. Dive into the world of DNA sequencing, discovering millions of genes and their potential impact on our understanding of life. Learn about the Sorcerer II Expedition's worldwide sampling route, the process of extracting genetic material, and the staggering amount of genetic code analyzed daily. Examine how water temperature affects biodiversity across different regions and understand the clustering of Global Ocean Sampling (GOS) sites. Delve into synthetic genomics, including chemical DNA synthesis, transposon mutagenesis, and the construction of artificial chromosomes. Investigate the potential of genome transplantation, combinatorial genomics, and the production of hydrogen through photosynthesis in cyanobacteria. Consider the ethical implications and policy studies surrounding these groundbreaking advancements in genomics and biotechnology.
Overview
Syllabus
Intro
Microbial Abundance
Sorcerer II Expedition World Sampling Route
Sample Fractionation
100 Million Letters of Genetic Code Every 24 Hours
Extraction of SpinCon Samples
The Biodiversity of Each New Region is Different
Water Temperature: Nova Scotia through Galapagos Islands
Clustering of GOS sites: Reads incorporated into significant scaffolds
Comprehensive Study
Number of Protein Families on Earth
Synthetic Genomics
Chemical Synthesis of DNA: From Genes to Genomes
Transposon (Tn4001) Mutagenesis
The Core Mycoplasma Genome is the Set of Genes Common to all 13 Complete Sequences
Construction of an Artificial Chromosome
From Reading to Writing: What can be made and when?
How Do We Connect Many Small Synthetic Genome Fragments into a Single Circular Chromosome?
Genome Transplantation
Combinatorial Genomics
Photosynthetic Production of Hydrogen in Cyanobacteria
Cellulase Team Technical Approach
Ethics and Policy Studies
Taught by
TED
