Overview
Syllabus
Intro
Disclosures
OBJECTIVES
Why is it Important to Know About CBC?
Treatment Preference
Increase in Bilateral Mastectomy Rates
Bilateral Mastectomy Rates are Age Dependent
Overall Surgery Trends for Stage 1-1 Breast Cancer Patients
Risk Factors for CBC
CBC Risk-Clinical Trials
Decreasing CBC with Anti-Estrogen Treatment (ER+ Tumors)
RISK OF CBC and RADIATION THERAPY FOR BREAST CANCER
CBC Risk and Family History Ten Year Cumulative Risks
CBC RISK in BRCA MUTATION CARRIERS-META-ANALYSIS of 20 STUDIES
CBC risk for Non-BRCA Genes
Prevalence of Genetic Mutations 2012-2015
Prevalence of Genetic Mutations by Race/Ethnicity
Conclusions
Manchester Guidelines
CBC Prediction Models
Clinical Application-CBC Prediction
CBC and Survival
Association of CPM with Reduction in Mortality Selection Bias Stage
BRCA carriers and Survival with Bilateral Mastectomy
Why Patients Choose CPM
THANK YOU
Taught by
Ambry Genetics